1

I am looking to build and maintain a database of newly approved oncology drugs from the FDA.

I need something similar to their "What's new" or "Novel Drug Approvals" section on their site. https://www.fda.gov/drugs/new-drugs-fda-cders-new-molecular-entities-and-new-therapeutic-biological-products/novel-drug-approvals-2020

I am not interested as much in shortages, recalls, etc.

My questions is (a) which openFDA endpoint do I need (Drugs@FDA? Product labeling?)? and (b) will this endpoint have the fields I need / is there a way to get the fields I need?

I am interested in getting

  • generic name for a given drug
  • tissue type or oncotree type the drug applies to
  • some sort of open text field regarding the "-INDICATIONS AND USAGE-" section of the prescribing info that I can use to mine relevant genes and/or conditions relating to the drug.

I feel like this should be possible and this information should be available but I am a bit confused by openFDA as a whole right now.

Additionally there seems to be many RSS feeds on the FDA site but there isn't one that seems to correlate to the FDA Drugs emails I subscribe to (Drugs / Oncology Drugs). If there was such a feed, I could use the drug names from that to query Drugs@FDA.

0

openFDA does not have an easy way to provide 100% accurate results to your query, but you could search the Drug Label endpoint and get "new" labels by filtering on effective_time and also looking in indications_and_usage for indications of a cancer drug, for example:

https://api.fda.gov/drug/label.json?search=indications_and_usage:%22cancer%22+AND+effective_time:[20210101+TO+20211231]+AND+openfda.product_type.exact:%22HUMAN%20PRESCRIPTION%20DRUG%22&sort=effective_time:desc&limit=100

Then you would need to cross-check the results with the Drugs@FDA endpoint to make sure the drugs in fact have had a recent FDA approval.

Your Answer

By clicking “Post Your Answer”, you agree to our terms of service, privacy policy and cookie policy

Not the answer you're looking for? Browse other questions tagged or ask your own question.